Journal
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Volume 19, Issue 1, Pages 36-39Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.seizure.2009.10.009
Keywords
Ketogenic diet; Ketosis; Beta-hydroxybutyrate; Parameter; Efficacy
Categories
Ask authors/readers for more resources
Purpose: To investigate whether it is better to use blood beta-hydroxybutyrate (BHB) or urinary ketones to monitor ketogenic diet (KD). Method: In 33 patients on KID we measured ketosis in two different ways. At the 3-monthly visits to the clinic we measured BHB in capillary blood obtained by finger-prick and the level of ketones in the urine using a urine dipstick. If the patient was able to collect urine, the urinary ketones were also measured every day at home. We compared the degree of ketosis with seizure reduction. Results: BHB measured during the 3-monthly visits correlated with seizure reduction at 3 and 6 months (p = 0.037 and 0.019, respectively). Urinary ketones measured at the same time did not correlate at any visit. The averaged values of the daily measured ketones in the urine did not correlate either. Conclusions: BHB correlates better with seizure reduction than do ketones in urine. It is, therefore, better to use BHB to monitor KID even if BHB is measured less frequently than urinary ketones. (C) 2009 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available