Journal
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Volume 19, Issue 8, Pages 525-528Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.seizure.2010.06.015
Keywords
Seizures; Epilepsy; Multiple sclerosis; EEG-fMRI; Cortical plaque
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Funding
- Emilia-Romagna Region, Italy
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A case of focal inferior limb sensory-motor status epilepticus as the only manifestation of a multiple sclerosis (MS) relapse is described. To obtain evidence of the relationship between the seizures, the cortical plaque and the left foot motor area, an EEG-fMRI co-registration study was undertaken demonstrating that seizure-related BOLD signal substantially overlapped with the inflammatory lesion involving the foot sensory-motor cortex. Seizures did not respond to intravenous anti-epileptic drugs (AEDs) but were controlled by steroid therapy. (C) 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
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