Related references
Note: Only part of the references are listed.Parenteral Ascorbate As a Cancer Therapeutic: A Reassessment Based on Pharmacokinetics
Nermi L. Parrow et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial
J. L. Welsh et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2013)
Autophagy and genomic integrity
A. T. Vessoni et al.
CELL DEATH AND DIFFERENTIATION (2013)
Various modes of cell death induced by DNA damage
O. Surova et al.
ONCOGENE (2013)
DNA damage associated with mitosis and cytokinesis failure
M. T. Hayashi et al.
ONCOGENE (2013)
Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest
Patries M. Herst et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer
Daniel A. Monti et al.
PLOS ONE (2012)
Intracellular ATP levels determine cell death fate of cancer cells exposed to both standard and redox chemotherapeutic agents
Julien Verrax et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs
Anja Froemberg et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer
Michael Graham Espey et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Vitamin C: A Concentration-Function Approach Yields Pharmacology and Therapeutic Discoveries
Mark Levine et al.
ADVANCES IN NUTRITION (2011)
Ascorbate induces autophagy in pancreatic cancer
Joseph J. Cullen
AUTOPHAGY (2010)
Pemetrexed Indirectly Activates the Metabolic Kinase AMPK in Human Carcinomas
Scott B. Rothbart et al.
CANCER RESEARCH (2010)
Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer
Juan Du et al.
CLINICAL CANCER RESEARCH (2010)
Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects
Sebastian J. Padayatty et al.
PLOS ONE (2010)
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
Angela Alexander et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
被撤回的出版物: A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress (Retracted article. See vol. 17, pg. 1944, 2010)
Q. Huang et al.
CELL DEATH AND DIFFERENTIATION (2009)
Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects
Julien Verrax et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Changing the Paradigm in the Treatment of Platinum-Sensitive Recurrent Ovarian Cancer From Platinum Doublets to Nonplatinum Doublets and Adding Antiangiogenesis Compounds
Bradley J. Monk et al.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2009)
Phase I clinical trial of i.v. ascorbic acid in advanced malignancy
L. J. Hoffer et al.
ANNALS OF ONCOLOGY (2008)
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Sodium ascorbate induces apoptosis in neuroblastoma cell lines by interfering with iron uptake
Roberta Carosio et al.
MOLECULAR CANCER (2007)
Tumor suppressor 101F6 and ascorbate synergistically and selectively inhibit non-small cell lung cancer growth by caspase-independent apoptosis and autophagy
Shoichiro Ohtani et al.
CANCER RESEARCH (2007)
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells
Shuw-Yuan Lin et al.
MELANOMA RESEARCH (2006)
Intravenously administered vitamin C as cancer therapy: three cases
SJ Padayatty et al.
CANADIAN MEDICAL ASSOCIATION JOURNAL (2006)
Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells
J Wendt et al.
ONCOGENE (2006)
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
Ting-Chao Chou
PHARMACOLOGICAL REVIEWS (2006)
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues
Q Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells.: An in vitro comparative study
F Verrax et al.
FREE RADICAL RESEARCH (2005)
Vitamin C pharmacokinetics: Implications for oral and intravenous use
SJ Padayatty et al.
ANNALS OF INTERNAL MEDICINE (2004)
Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death
J Verrax et al.
APOPTOSIS (2004)
The use of antioxidants with first-line chemotherapy in two cases of ovarian cancer
JA Drisko et al.
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2003)
L-Ascorbic acid (vitamin C) induces the apoptosis of B16 murine melanoma cells via a caspase-8-independent pathway
JS Kang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2003)
A modified neutral comet assay:: elimination of lysis at high temperature and validation of the assay with anti-single-stranded DNA antibody
M Wojewódzka et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2002)
Ultrastructural aspects of autoschizis: A new cancer cell death induced by the synergistic action of ascorbate/menadione on human bladder carcinoma cells
J Gilloteaux et al.
ULTRASTRUCTURAL PATHOLOGY (2001)
In vivo reactivation of DNases in implanted human prostate tumors after administration of a vitamin C/K-3 combination
HS Taper et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2001)
Share Paper
