4.8 Article

Evaluating Preclinical Efficacy

Journal

SCIENCE TRANSLATIONAL MEDICINE
Volume 3, Issue 96, Pages -

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.3002757

Keywords

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Funding

  1. NIH
  2. JDRF
  3. American Diabetes Association
  4. Brehm Coalition for Type 1 Diabetes Research
  5. Jeffrey Keene Family Professorship

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Recent disappointing results of clinical trials seeking type 1 diabetes (T1D) reversal suggest the need for a reevaluation of our translational efforts. This Commentary explores the need for standards in evaluating therapeutic efficacy in preclinical models of T1D.

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