Journal
SCIENCE TRANSLATIONAL MEDICINE
Volume 2, Issue 15, Pages -Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.3000361
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Funding
- NCRR NIH HHS [UL1 RR025014-03, TL1 RR025016, KL2 RR025015, TL1 RR025016-03, KL2 RR025015-03, TL1 RR 025016, UL1 RR025014, KL2 RR 025015] Funding Source: Medline
- NHGRI NIH HHS [P50 HG003374] Funding Source: Medline
- NIEHS NIH HHS [P30 ES07033, P30 ES007033] Funding Source: Medline
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Advances in clinical translational research have led to an explosion of interest in infrastructure development and data sharing facilitated by biorepositories of specimens and linked health information. These efforts are qualitatively different from the single-center sample collections that preceded them and pose substantial new ethics and regulatory challenges for investigators and institutions. New research governance approaches, which can address current and anticipated challenges, promote high-quality research, and provide a robust basis for ongoing research participation, are urgently required.
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