4.5 Editorial Material

Using Partial Least Squares Regression to Analyze Cellular Response Data

Journal

SCIENCE SIGNALING
Volume 6, Issue 271, Pages -

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scisignal.2003849

Keywords

PLSR; multivariate analysis; systems biology; computational biology; cancer therapy

Funding

  1. NSF [CBET-0951613]
  2. Div Of Chem, Bioeng, Env, & Transp Sys
  3. Directorate For Engineering [0951613] Funding Source: National Science Foundation

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This Teaching Resource provides lecture notes, slides, and a problem set for a lecture introducing the mathematical concepts and interpretation of partial least squares regression (PLSR) that were part of a course entitled Systems Biology: Mammalian Signaling Networks. PLSR is a multivariate regression technique commonly applied to analyze relationships between signaling or transcriptional data and cellular behavior.

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