4.5 Article

An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt

Related references

Note: Only part of the references are listed.
Letter Biochemical Research Methods

Data transformation practices in biomedical sciences

Mihai Valcu et al.

NATURE METHODS (2011)

Article Medicine, General & Internal

A Mosaic Activating Mutation in AKT1 Associated with the Proteus Syndrome

Marjorie J. Lindhurst et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Multidisciplinary Sciences

Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity

Tung O. Chan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Chemistry, Medicinal

Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

Josef R. Bencsik et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Article Chemistry, Medicinal

Discovery of pyrrolopyrimidine inhibitors of Akt

James F. Blake et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Review Pharmacology & Pharmacy

Akt inhibitors in clinical development for the treatment of cancer

Sumanta Kumar Pal et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)

Article Biochemistry & Molecular Biology

Inhibitor hijacking of Akt activation

Tatsuya Okuzumi et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Chemistry, Medicinal

Allosteric inhibitors of Akt1 and Akt2: A naphthyridinone with efficacy in an A2780 tumor xenograft model

Mark T. Bilodeau et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Article Multidisciplinary Sciences

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

John D. Carpten et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo

Veronique Calleja et al.

PLOS BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Rational design of inhibitors that bind to inactive kinase conformations

Y Liu et al.

NATURE CHEMICAL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

Perturbations of the AKT signaling pathway in human cancer

DA Altomare et al.

ONCOGENE (2005)

Article Biochemistry & Molecular Biology

Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1

RI Feldman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

DD Sarbassov et al.

SCIENCE (2005)

Article Chemistry, Medicinal

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

CW Lindsley et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

J Yang et al.

NATURE STRUCTURAL BIOLOGY (2002)

Review Endocrinology & Metabolism

Role of Akt/protein kinase B in metabolism

EL Whiteman et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2002)