Related references
Note: Only part of the references are listed.Daily injections of the glutathione disulfide mimetic NOV-002 ameliorates hematologic toxicities from neoadjuvant chemotherapy in breast cancer patients enrolled in the NEO-NOVO trial, and significantly increases circulating dendritic cells.
C Diaz-Montero et al.
CANCER RESEARCH (2010)
Phosphotyrosine Signaling: Evolving a New Cellular Communication System
Wendell A. Lim et al.
CELL (2010)
Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II
Marie-Laure Diebold et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)
Mai Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity
Bernard A. Liu et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Designing customized cell signalling circuits
Wendell A. Lim
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity
John Colicelli
SCIENCE SIGNALING (2010)
Genomic and structural aspects of protein evolution
Cyrus Chothia et al.
BIOCHEMICAL JOURNAL (2009)
Tyrosine-phosphorylation: thirty years and counting
Tony Hunter
CURRENT OPINION IN CELL BIOLOGY (2009)
SLAP, a regulator of immunoreceptor ubiquitination, signaling, and trafficking
Leonard L. Dragone et al.
IMMUNOLOGICAL REVIEWS (2009)
Structure and in Vivo Requirement of the Yeast Spt6 SH2 Domain
Stefan Dengl et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases
David M. A. Martin et al.
NUCLEIC ACIDS RESEARCH (2009)
Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases
Chris Soon Heng Tan et al.
SCIENCE SIGNALING (2009)
Eukaryotic Protein Domains as Functional Units of Cellular Evolution
Jing Jin et al.
SCIENCE SIGNALING (2009)
Cell-cell adhesion in the Cnidaria: Insights into the evolution of tissue morphogenesis
Craig R. Magie et al.
BIOLOGICAL BULLETIN (2008)
Genome duplication and the origin of the vertebrate skeleton
GuangJun Zhang et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)
Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation
Wanqing Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A Dictyostelium homologue of the metazoan Cbl proteins regulates STAT signalling
Judith Langenick et al.
JOURNAL OF CELL SCIENCE (2008)
Gene expansion and retention leads to a diverse tyrosine kinase superfamily in amphioxus
Salvatore D'Aniello et al.
MOLECULAR BIOLOGY AND EVOLUTION (2008)
The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
Nicole King et al.
NATURE (2008)
The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan
Gerard Manning et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages
David Pincus et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Linear Motif Atlas for Phosphorylation-Dependent Signaling
Martin Lee Miller et al.
SCIENCE SIGNALING (2008)
Arrangements in the modular evolution of proteins
Andrew D. Moore et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
The Pfam protein families database
Robert D. Finn et al.
NUCLEIC ACIDS RESEARCH (2008)
Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation
Alex N. Bullock et al.
STRUCTURE (2007)
Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7
Brandon E. Kremer et al.
CELL (2007)
Classification and functional annotation of eukaryotic protein kinases
Diego Miranda-Saavedra et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
MEGA4: Molecular evolutionary genetics analysis (MEGA) software version 4.0
Koichiro Tamura et al.
MOLECULAR BIOLOGY AND EVOLUTION (2007)
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK
Yoshihiro Kobashigawa et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
External factors accelerate expression divergence between duplicate genes
Misook Ha et al.
TRENDS IN GENETICS (2007)
Modeling the evolution of protein domain architectures using maximum parsimony
Jessica H. Fong et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export
Sunnie M. Yoh et al.
GENES & DEVELOPMENT (2007)
The blood/vascular system in a phylogenetic perspective
Volker Hartenstein et al.
BIOESSAYS (2006)
The sea urchin kinoine: A first look
Cynthia A. Bradham et al.
DEVELOPMENTAL BIOLOGY (2006)
Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays
Matthew J. Smith et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Functional development of Src tyrosine kinases during evolution from a unicellular ancestor to multicellular animals
Yuko Segawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The human and mouse complement of SH2 domain proteins -: Establishing the boundaries of phosphotyrosine signaling
Bernard A. Liu et al.
MOLECULAR CELL (2006)
Protein family expansions and biological complexity
Christine Vogel et al.
PLOS COMPUTATIONAL BIOLOGY (2006)
A WNT of things to come: Evolution of Wnt signaling and polarity in cnidarians
Patricia N. Lee et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2006)
The Dictyostelium kinome -: Analysis of the protein kinases from a simple model organism
Jonathan M. Goldberg et al.
PLOS GENETICS (2006)
SMART 5: domains in the context of genomes and networks
Ivica Letunic et al.
NUCLEIC ACIDS RESEARCH (2006)
Immune regulation by SLAM family receptors and SAP-related adaptors
A Veillette
NATURE REVIEWS IMMUNOLOGY (2006)
Expression divergence between duplicate genes
WH Li et al.
TRENDS IN GENETICS (2005)
Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor
R Roncagalli et al.
NATURE IMMUNOLOGY (2005)
Manifestations of multicellularity:: Dictyostelium reports in
JG Williams et al.
TRENDS IN GENETICS (2005)
The C2 domain of PKCδ is a phosphotyrosine binding domain
CH Benes et al.
CELL (2005)
SH2 domains in plants imply new signalling scenarios
JG Williams et al.
TRENDS IN PLANT SCIENCE (2004)
Multivesicular body sorting: Ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S
DJ Katzmann et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Specificity in signal transduction: From phosphotyrosine-SH2 domain interactions to complex cellular systems
T Pawson
CELL (2004)
Protein domains correlate strongly with exons in multiple eukaryotic genomes - evidence of exon shuffling?
MY Liu et al.
TRENDS IN GENETICS (2004)
The SAP family of adaptors in immune regulation
S Latour et al.
SEMINARS IN IMMUNOLOGY (2004)
Identification of the linker-SH2 domain of STAT as the origin of the SH2 domain using two-dimensional structural alignment
Q Gao et al.
MOLECULAR & CELLULAR PROTEOMICS (2004)
Origins, lineage-specific expansions, and multiple losses of tyrosine kinases in eukaryotes
SH Shiu et al.
MOLECULAR BIOLOGY AND EVOLUTION (2004)
An ancient role for nuclear β-catenin in the evolution of axial polarity and germ layer segregation
AH Wikramanayake et al.
NATURE (2003)
The FRK/RAK-SHB signaling cascade:: A versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation
C Annerén et al.
CURRENT MOLECULAR MEDICINE (2003)
Assembly of cell regulatory systems through protein interaction domains
T Pawson et al.
SCIENCE (2003)
Molecular evolution meets the genomics revolution
KH Wolfe et al.
NATURE GENETICS (2003)
Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors
CJ Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
SAP couples Fyn to SLAM immune receptors
B Chan et al.
NATURE CELL BIOLOGY (2003)
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation
S Latour et al.
NATURE CELL BIOLOGY (2003)
Regulation of JAK-STAT signalling in the immune system
K Shuai et al.
NATURE REVIEWS IMMUNOLOGY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Splitting pairs: The diverging fates of duplicated genes
VE Prince et al.
NATURE REVIEWS GENETICS (2002)
Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
LW Donaldson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Evolution of protein kinase signaling from yeast to man
G Manning et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Adaptive evolution after gene duplication
AL Hughes
TRENDS IN GENETICS (2002)
IL-2 receptor signaling through the Shb adapter protein in T and NK cells
CK Lindholm
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells
CK Lindholm et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Regulation of the immune response by SHIP
ME March et al.
SEMINARS IN IMMUNOLOGY (2002)
The phagotrophic origin of eukaryotes and phylogenetic classification of protozoa
T Cavalier-Smith
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY (2002)
A receptor tyrosine kinase from choanoflagellates: Molecular insights into early animal evolution
N King et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor
T Miyoshi-Akiyama et al.
ONCOGENE (2001)
Tyrosine phosphorylation-independent nuclear translocation of a Dictyostelium STAT in response to DIF signaling
M Fukuzawa et al.
MOLECULAR CELL (2001)
Requirement for the SLP-76 adaptor CADS in T cell development
J Yoder et al.
SCIENCE (2001)
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
T Sosinowski et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Share Paper
