4.7 Article

Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The Glutamate Hypothesis in ALS: Pathophysiology and Drug Development

H. Blasco et al.

CURRENT MEDICINAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Recent Development of Multifunctional Agents as Potential Drug Candidates for the Treatment of Alzheimer’s Disease

Natalia Guzior et al.

CURRENT MEDICINAL CHEMISTRY (2014)

Article Neurosciences

Cholinesterase Inhibition in Alzheimer's Disease: Is Specificity the Answer?

Ian R. Macdonald et al.

JOURNAL OF ALZHEIMERS DISEASE (2014)

Article Biochemistry & Molecular Biology

Determination of binding points of methylene blue and cationic phenoxazine dyes on human butyrylcholinesterase

Zeynep Sezgin et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2013)

Article Biochemistry & Molecular Biology

Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors

Lyudmila G. Tsurkan et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2013)

Article Biochemistry & Molecular Biology

Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects

Galina F. Makhaeva et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2013)

Article Biochemistry & Molecular Biology

Rationally Designed Multi-Targeted Agents Against Neurodegenerative Diseases

W. J. Geldenhuys et al.

CURRENT MEDICINAL CHEMISTRY (2013)

Review Chemistry, Medicinal

The Multifactorial Nature of Alzheimer's Disease for Developing Potential Therapeutics

M. Carmo Carreiras et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)

Review Pharmacology & Pharmacy

The Role of Human Carboxylesterases in Drug Metabolism: Have We Overlooked Their Importance?

S. Casey Laizure et al.

PHARMACOTHERAPY (2013)

Article Chemistry, Multidisciplinary

Molecular modeling of butyrylcholinesterase inhibition by cresyl saligenin phosphate

S. V. Lushchekina et al.

RUSSIAN CHEMICAL BULLETIN (2013)

Review Pharmacology & Pharmacy

New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs

Salvatore Salomone et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2012)

Review Clinical Neurology

Rationale for combining glutamatergic and cholinergic approaches in the symptomatic treatment of Alzheimer's disease

Paul T. Francis et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2012)

Editorial Material Medicine, General & Internal

Cholinesterase inhibitors and memantine for symptomatic treatment of dementia

Joanne Rodda et al.

BMJ-BRITISH MEDICAL JOURNAL (2012)

Article Biochemistry & Molecular Biology

Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants

Sultan Darvesh et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2010)

Review Neurosciences

Protective Role of Methylene Blue in Alzheimer's Disease via Mitochondria and Cytochrome c Oxidase

Hani Atamna et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Pharmacology & Pharmacy

Methylene blue and Alzheimer's disease

Murat Oz et al.

BIOCHEMICAL PHARMACOLOGY (2009)

Article Clinical Neurology

Different Cholinesterase Inhibitor Effects on CSF Cholinesterases in Alzheimer Patients

Agneta Nordberg et al.

CURRENT ALZHEIMER RESEARCH (2009)

Article Biochemistry & Molecular Biology

Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models

Makiko Yamashita et al.

FEBS LETTERS (2009)

Review Clinical Neurology

Amyotrophic lateral sclerosis: A 40-year personal perspective

Andrew Eisen

JOURNAL OF CLINICAL NEUROSCIENCE (2009)

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Rational design of a drug for Alzheimer's disease with cholinesterase inhibitory and neuroprotective activity

M. Weinstock et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2008)

Article Clinical Neurology

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

Elliott J Mufson et al.

Expert Review of Neurotherapeutics (2008)

Article Chemistry, Medicinal

Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase

Sultan Darvesh et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine

Sultan Darvesh et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2007)

Article Pharmacology & Pharmacy

Rationale for combination therapy with galantamine and Memantine in Alzheimer's disease

George T. Grossberg et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2006)

Review Clinical Neurology

Targeting acetylcholinesterase and butyrylcholinesterase in dementia

RM Lane et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2006)

Review Pharmacology & Pharmacy

Human carboxylesterase isozymes: Catalytic properties and rational drug design

Teruko Imai

DRUG METABOLISM AND PHARMACOKINETICS (2006)

Review Pharmacology & Pharmacy

Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease

A Martinez et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2006)

Article Multidisciplinary Sciences

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

NH Greig et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives

S Darvesh et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products

Y Nicolet et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Medicine, Research & Experimental

Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons

VV Grigor'ev et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2003)

Article Biochemistry & Molecular Biology

The Protein Data Bank

HM Berman et al.

NUCLEIC ACIDS RESEARCH (2000)