Size dependent magnetic hyperthermia of octahedral Fe3O4 nanoparticles

Magnetic nanoparticle hyperthermia is promising as a cancer therapeutic treatment. Shape and size are two crucial factors for the magnetic hyperthermia performance of nanoparticles. In this work, octahedral Fe3O4 nanoparticles with different sizes are successfully synthesized and their magnetic hyperthermia performances are investigated systematically in a gel suspension. The results suggest a wide size range (43-98 nm) for high SAR values (up to 2629 W g(-1)). The SAR values are verified by hysteresis loss measured in the gel suspension. This study demonstrates that octahedral Fe3O4 nanoparticles can serve as an excellent thermal seed for high performance magnetic hyperthermia cancer treatment.