4.6 Article

Benzyl bromides as aroyl surrogates in substrate directed Pd catalysed o-aroylation

Journal

RSC ADVANCES
Volume 5, Issue 42, Pages 33334-33338

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra03836g

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Funding

  1. Science and Engineering Research Board (SERB), New Delhi [SB/S1/OC-53/2013]
  2. Council of Scientific and Industrial Research (CSIR) [02(0096)/12/EMR-II]

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An oxidative cross-coupling between directing substrates and benzyl bromides via the combined effect of oxidants TBHP and NMO, catalysed by Pd(II) has been investigated. Benzyl bromides served as efficient aroyl surrogates in this substrate directed C-H functionalisation. The in situ generated benzaldehyde originating from benzyl bromide is the active aroylating source.

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