4.6 Review

Research progress of nanoparticles as enzyme mimetics

Journal

SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY
Volume 54, Issue 10, Pages 1749-1756

Publisher

SCIENCE PRESS
DOI: 10.1007/s11433-011-4480-0

Keywords

artificial enzyme mimetics; Fe3O4 nanoparticles; CeO2 nanoparticles; Pt nanoparticles; biodetection

Funding

  1. National Natural Science Foundation of China [20773032]
  2. National Basic Research Program of China [2011CB932802]

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Natural enzymes as biological catalysts possess remarkable advantages, especially their highly efficient and selective catalysis under mild conditions. However, most natural enzymes are proteins, thus exhibiting an inherent low durability to harsh reaction conditions. Artificial enzyme mimetics have been pursued extensively to avoid this drawback. Quite recently, some inorganic nanoparticles (NPs) have been found to exhibit unique enzyme mimetics. In addition, their much higher stability overcomes the inherent disadvantage of natural enzymes. Furthermore, easy mass-production and low cost endow them more benefits. As a new member of artificial enzyme mimetics, they have received intense attention. In this review article, major progress in this field is summarized and future perspectives are highlighted.

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