Journal
SCIENCE CHINA-CHEMISTRY
Volume 58, Issue 4, Pages 684-688Publisher
SCIENCE PRESS
DOI: 10.1007/s11426-014-5158-z
Keywords
radical reaction; C-H cyclization; Meerwein arylation; oxindole; copper-catalyzed
Categories
Funding
- National Natural Science Foundation of China [21462017]
- China Posdoctoral Science Foundation [2014M560649]
- Scientific Research Fund of Hunan Provincial Education Department [13B094]
- Fund of Science and Technology Innovation and Entrepreneur for Hunan Young Talents
- Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
Ask authors/readers for more resources
A simple and direct route for double C-C bond formation by copper-catalyzed Meerwein carboarylation process has been developed. In the presence of CuI (5 mol%), tert-butyl nitrite and anilines, a wide variety of N-arylacrylamides underwent tandem Meerwein arylation/C-H cyclization to produce pharmaceutically important 3-benzyl-3-alkyloxindole in moderate to good yield.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
