The synthesis of benzoxaboroles and their applications in medicinal chemistry

Benzoxaborole, as a versatile scaffold, plays important roles in organic synthesis, molecular recognition and supramolecular chemistry. It is also a privileged structure in medicinal chemistry due to its desirable physicochemical and drug-like properties. Recently, benzoxaboroles were widely applied as antifungal, antibacterial, antiviral, anti-parasite, and anti-inflammatory agents. This review covers the properties, synthetic methods and applications of benzoxaboroles in medicinal chemistry.