Journal
SCIENCE CHINA-CHEMISTRY
Volume 55, Issue 5, Pages 772-778Publisher
SCIENCE PRESS
DOI: 10.1007/s11426-012-4528-7
Keywords
amphiphilic polymer; aggregation-induced emission; tetraphenylethene; self-assembly; cell imaging
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Funding
- National Natural Science Foundation of China [20974028, 20974098, 21174120]
- National Basic Research Program of China [2009CB623605]
- Research Grants Council of Hong Kong [603509, HKUST2/CRF/10, 604711, N_HKUST620/11]
- Cao Guangbiao Foundation of Zhejiang University
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An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.
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