Journal
SCIENCE CHINA-CHEMISTRY
Volume 53, Issue 11, Pages 2226-2232Publisher
SCIENCE PRESS
DOI: 10.1007/s11426-010-4142-5
Keywords
nanotechnology; nanoparticles; multidrug resistance; chemotherapeutic drugs; cancer; drug delivery system
Categories
Funding
- National Basic Research Program of China [2010CB934000]
- National Natural Science Foundation of China [30925041]
- Shanghai Nanomedicine Program [0852nm05700]
Ask authors/readers for more resources
The emerging nanotechnology-based drug delivery holds tremendous potential to deliver chemotherapeutic drugs for treatment of multidrug resistance (MDR) cancer. This drug delivery system could improve the pharmacokinetic behavior of antitumor drugs, deliver chemotherapeutic drugs to target sites, control release of drugs, and reduce the systemic toxicity of drugs in MDR cancer. This review addresses the use of nanotechnology to overcome MDR classified on the bases of the fundamental mechanisms of MDR and various approaches to deliver drugs for treatment of MDR cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
