Journal
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
Volume 10, Issue 1, Pages -Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1088/1468-6996/10/1/014611
Keywords
diamagnetic repulsion; continuous flow; microfluidic; microparticles; superconducting magnet
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Funding
- EPSRC [EP/E065414/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/E065414/1] Funding Source: researchfish
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We explore the potential of a microfluidic continuous flow particle separation system based on the repulsion of diamagnetic materials from a high magnetic field. Diamagnetic polystyrene particles in paramagnetic manganese (II) chloride solution were pumped into a microfluidic chamber and their deflection behaviour in a high magnetic field applied by a superconducting magnet was investigated. Two particle sizes (5 and 10 mu m) were examined in two concentrations of MnCl2 (6 and 10%). The larger particles were repelled to a greater extent than the smaller ones, and the effect was greatly enhanced when the particles were suspended in a higher concentration of MnCl2. These findings indicate that the system could be viable for the separation of materials of differing size and/or diamagnetic susceptibility, and as such could be suitable for the separation and sorting of small biological species for subsequent studies.
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