4.8 Article

Yeast Reveal a Druggable Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

Helga Thorvaldsdottir et al.

BRIEFINGS IN BIOINFORMATICS (2013)

Review Biochemistry & Molecular Biology

An ERcentric view of Parkinson's disease

Gabriela Mercado et al.

TRENDS IN MOLECULAR MEDICINE (2013)

Article Developmental Biology

Synaptic vesicle trafficking and Parkinson's disease

Giovanni Esposito et al.

DEVELOPMENTAL NEUROBIOLOGY (2012)

Article Biochemistry & Molecular Biology

Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct Mechanisms

Daniel F. Tardiff et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Genetics & Heredity

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

Alexander Zimprich et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Article Genetics & Heredity

VPS35 Mutations in Parkinson Disease

Carles Vilarino-Gueell et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Editorial Material Cell Biology

The Parkinson disease protein α-synuclein inhibits autophagy

Ashley R. Winslow et al.

AUTOPHAGY (2011)

Article Biochemistry & Molecular Biology

Structure and function of a HECT domain ubiquitin-binding site

Hyung Cheol Kim et al.

EMBO REPORTS (2011)

Article Biochemistry & Molecular Biology

Aggregation of α-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis

James H. Soper et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2011)

Article Genetics & Heredity

A framework for variation discovery and genotyping using next-generation DNA sequencing data

Mark A. DePristo et al.

NATURE GENETICS (2011)

Article Biotechnology & Applied Microbiology

How were new medicines discovered?

David C. Swinney et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Multidisciplinary Sciences

Ubiquitin ligase Nedd4 promotes α-synuclein degradation by the endosomal-lysosomal pathway

George K. Tofaris et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemistry & Molecular Biology

A Yeast Model of FUS/TLS-Dependent Cytotoxicity

Shulin Ju et al.

PLOS BIOLOGY (2011)

Article Biochemistry & Molecular Biology

A Saccharomyces cerevisiae strain unable to store neutral lipids is tolerant to oxidative stress induced by α-synuclein

Yves Y. Sere et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Neurosciences

OPINION Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?

Vikram Khurana et al.

NATURE REVIEWS NEUROSCIENCE (2010)

Review Pharmacology & Pharmacy

A survey of yeast genomic assays for drug and target discovery

Andrew M. Smith et al.

PHARMACOLOGY & THERAPEUTICS (2010)

Article Multidisciplinary Sciences

Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

Molly A. Lynch-Day et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Cell Biology

The ubiquitin code of yeast permease trafficking

Elsa Lauwers et al.

TRENDS IN CELL BIOLOGY (2010)

Article Biochemical Research Methods

Fast and accurate short read alignment with Burrows-Wheeler transform

Heng Li et al.

BIOINFORMATICS (2009)

Review Cell Biology

Physiological functions of the HECT family of ubiquitin ligases

Daniela Rotin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Impairment of microtubule system increases α-synuclein aggregation and toxicity

Myunghye Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Article Biochemistry & Molecular Biology

Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson

Piotr Zabrocki et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)

Article Biochemistry & Molecular Biology

Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults

Fang Liu et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Article Cell Biology

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

Martin L. Duennwald et al.

GENES & DEVELOPMENT (2008)

Article Multidisciplinary Sciences

The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis

Aaron D. Gitler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

Antony A. Cooper et al.

SCIENCE (2006)

Article Multidisciplinary Sciences

A network of protein interactions determines polyglutamine toxicity

Martin L. Duennwald et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

alpha-synuclein budding yeast model - Toxicity enhanced by impaired proteasome and oxidative stress

N Sharma et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2006)

Article Biochemistry & Molecular Biology

Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease

TR Flower et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Yeast cells provide insight into alpha-synuclein biology and pathobiology

TF Outeiro et al.

SCIENCE (2003)

Article Multidisciplinary Sciences

α-synuclein locus triplication causes Parkinson's disease

AB Singleton et al.

SCIENCE (2003)