Journal
RSC ADVANCES
Volume 5, Issue 6, Pages 4484-4488Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra13097a
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Primary thioamides have been utilised directly in water, without any derivatisation, to selectively thioacylate primary amines. By employing 2-hydroxyethylamines, the reaction can be extended to the preparation of 2-thiazolines via formation of beta-hydroxythioamides.
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