4.8 Editorial Material

Innate Immunity in Plants: An Arms Race Between Pattern Recognition Receptors in Plants and Effectors in Microbial Pathogens

Journal

SCIENCE
Volume 324, Issue 5928, Pages 742-744

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1171647

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Funding

  1. NIAID NIH HHS [R01 AI060761-04, R01AI060761, R01 AI060761] Funding Source: Medline

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For many years, research on a suite of plant defense responses that begin when plants are exposed to general microbial elicitors was underappreciated, for a good reason: There has been no critical experimental demonstration of their importance in mediating plant resistance during pathogen infection. Today, these microbial elicitors are named pathogen-or microbe-associated molecular patterns (PAMPs or MAMPs) and the plant responses are known as PAMP-triggered immunity (PTI). Recent studies provide an elegant explanation for the difficulty of demonstrating the role of PTI in plant disease resistance. It turns out that the important contribution of PTI to disease resistance is masked by pathogen virulence effectors that have evolved to suppress it.

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