Journal
SCHWEIZER ARCHIV FUR TIERHEILKUNDE
Volume 150, Issue 7, Pages 339-343Publisher
VERLAG HANS HUBER
DOI: 10.1024/0036-7281.150.7.339
Keywords
Staphylococcus pseudintermedius; leukocidin; methicillin-resistance; cat; urinary tract infection
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Methicillin resistance has emerged in clinical isolates of Staphylococcus pscudintermedius from cats in Switzerland. Three cats suffering from urinary tract infections were infected with methicillin-resistant S. pseudintermedius (MRSP). Phenotypic and genotypic Characterization of the resistance profile showed that the isolates displayed resistance to all beta-lactams and cephalosporins (blaZ, mecA), fluoroquinolones, tetracyclines [tet(K)], macrolides, lincosamides and I streprogramins B [erm(B)], chloramplicnicol (cat-(pC211)), trimethoprim [dfr(G)] and the aminoglycosides gentamicin [aac(6')-Ie-aph(2)-Ia], kanamycin and neomycin [aph(3')-III] and streptomycin [ant(6)-Ia]. They also harbor the leukocidin gene lukS-I. MRSP represents a new challenge for antibiotic therapy and this zoonotic bacteria may rapidly spread to animals and humans.
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