Journal
SCHIZOPHRENIA RESEARCH
Volume 191, Issue -, Pages 109-122Publisher
ELSEVIER
DOI: 10.1016/j.schres.2017.04.019
Keywords
Schizophrenia; MMN; Predictive coding; N1-suppression; Auditory oddball; Prodromal
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Funding
- University of Queensland [2016000071]
- University of Queensland International Research Scholarship
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Sensory prediction errors are fundamental brain responses that signal a violation of expectation in either the internal or external sensory environment, and are therefore crucial for survival and adaptive behaviour. Patients with schizophrenia show deficits in these internal and external sensory prediction errors, which can be measured using electroencephalography (EEG) components such as N1 and mismatch negativity (MMN), respectively. New evidence suggests that these deficits in sensory prediction errors are more widely distributed on a continuum of psychosis, whereas psychotic experiences exist to varying degrees throughout the general population. In this paper, we review recent findings in sensory prediction errors in the auditory domain across the continuum of psychosis, and discuss these in light of the predictive coding hypothesis. (c) 2017 Elsevier B.V. All rights reserved.
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