Journal
RSC ADVANCES
Volume 5, Issue 87, Pages 70718-70725Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra13932e
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Funding
- UGC, New Delhi
- DST, New Delhi
- PURSE program of the DST, New Delhi
- FIST program of the DST, New Delhi
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An efficient and ecofriendly synthesis of coumarin-3-carbamides, a class of compounds known for their remarkable biological activities and fluorescent properties, has been developed by a three-component reaction of 2-hydroxybenzaldehydes, aliphatic primary/secondary amines and diethyl malonate using Ni-NiO nanoparticles as catalyst in the green solvent ethanol. The method is compatible with various functional groups and moieties.
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