Journal
SCHIZOPHRENIA BULLETIN
Volume 38, Issue 4, Pages 695-703Publisher
OXFORD UNIV PRESS
DOI: 10.1093/schbul/sbs066
Keywords
hallucinations; neuroimaging; MRI; PET; DTI; MRS
Categories
Funding
- National Institute of Mental Health [R01 MH067073]
- Dana Foundation
- National Alliance for Research on Schizophrenia and Depression
- Pierre Hourriez Foundation
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Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.
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