4.6 Article

Visible light photoredox catalysis: regioselective radical addition of aminoalkyl radicals to 2,3-allenoates

Journal

RSC ADVANCES
Volume 5, Issue 68, Pages 55290-55294

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra10491b

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Funding

  1. Zhejiang Provincial Natural Science Foundation of China [LY15B020004]
  2. National Basic Research Program of China (973 Program) [2011CB710800]

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The regioselective addition of alpha-aminoalkyl radicals to 2,3-allenoates by visible-light-mediated electron transfer using 1 mol% of Ru(bpy)(3)(BF4)(2) as a photocatalyst was successfully established. This photoredox protocol is a simple and effective method for the synthesis of unsaturated g-aminobutyric ester derivatives.

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