3.9 Article

Necrotizing myositis and septic shock caused by Haemophilus influenzae type f in a previously healthy man diagnosed with an IgG3 and a mannose-binding lectin deficiency

Journal

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
Volume 43, Issue 11-12, Pages 972-976

Publisher

INFORMA HEALTHCARE
DOI: 10.3109/00365548.2011.589079

Keywords

Haemophilus influenzae; myositis; IgG3 deficiency; MBL deficiency

Funding

  1. Alfred Osterlund Foundation
  2. Anna and Edwin Berger Foundation
  3. Capio Research Foundation
  4. Greta and Johan Kock Foundation
  5. Gyllenstierna Krapperup Foundation
  6. Physiographical Society in Lund
  7. Cancer Foundation at the University Hospital in Malmo
  8. Skane County Council's Research and Development Foundation

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An increased incidence of infections by Haemophilus influenzae type f (Hif) has recently been suggested, but such infections have mainly been regarded as opportunistic. We present here a dramatic case of Hif necrotizing myositis and septic shock. A subsequently diagnosed IgG3 and mannose-binding lectin deficiency possibly contributed to the severe outcome.

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