Journal
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Volume 47, Issue 12, Pages 1480-1487Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/00365521.2012.733955
Keywords
gut-directed hypnotherapy; irritable bowel syndrome; manometry; transit investigation
Categories
Funding
- Vastra Gotaland Region (Dagmar funds)
- Swedish Research Council [13409, 21691, 21692]
- Marianne and Marcus Wallenberg Foundation
- University of Gothenburg, Centre for Person-Centred Care (GPCC)
- Sahlgrenska Academy
- Faculty of Medicine, University of Gothenburg
- Danone
- AstraZeneca
Ask authors/readers for more resources
Background. Gut-directed hypnotherapy is an effective treatment in irritable bowel syndrome (IBS) but little is known about the mechanisms of action. In this study we aimed to investigate the effects on gastrointestinal motility when treating IBS with gut-directed hypnotherapy. Methods. We randomized 90 patients with IBS, refractory to standard management to receive gut-directed hypnotherapy 1 h/week for 12 weeks or supportive treatment for the same time period. Eighty-one subjects (40 hypnotherapy, 41 controls) could be evaluated by one or more of the following investigations, both before and after the intervention: gastric emptying time, small bowel transit time, colonic transit time, and antroduodenojejunal manometry. Results. No significant differences in gastric emptying time, small bowel transit time, or colonic transit time was found when comparing the baseline and post-intervention measurements in the hypnotherapy group or in the control group. The same was true concerning the results of the antroduodenojejunal manometry. However, there was a numerical trend toward a higher number of migrating motor complexes at manometry and an accelerated gastric emptying time after hypnotherapy that did not reach statistical significance. Conclusions. In this study, we were not able to find evidence for long-standing effects on gastrointestinal motility as a mediator of the effects on IBS when treating the condition with gut-directed hypnotherapy. Further research to understand the mechanism of action is needed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available