Journal
RSC ADVANCES
Volume 5, Issue 92, Pages 75182-75186Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra13302e
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Funding
- National Natural Science Foundation of China [21332004, 21202055]
- Specialized Research Fund for the Doctoral Program of Higher Education [20201263001]
- Fok Ying-Tong Education Foundation [142017]
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An efficient one-pot, Pd(PPh3)(4) catalyzed, water-promoted method for the synthesis of N-(pyridin-2-ylmethyl) biphenyl-4-sulfonamides was developed under microwave irradiation. This methodology is acid free, has good substrate scope, excellent functional group compatibility, and excellent product yields, and is superior to the existing procedures for the synthesis of biphenyl-4-sulfonamides bearing a pyridin-2-ylmethyl group.
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