4.6 Article

PhI(OAc)(2)-promoted metal-free oxidation of 2-oxoaldehydes: a facile one-pot synthesis of cyanoformamides

Journal

RSC ADVANCES
Volume 5, Issue 101, Pages 82800-82803

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra14409d

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Funding

  1. National Natural Science Foundation of China (NSFC) [81373259, 81573286]

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A novel, efficient and environmental method for the conversion of 2-oxoaldehydes into cyanoformamides with iodosobenzene diacetate as oxidant has been developed. The reactions proceeded smoothly at room temperature under metal-free conditions and generated the corresponding products in good to excellent yields.

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