Journal
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 44, Issue 1, Pages 124-127Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1070428008010168
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A procedure has been proposed for the selective preparation of Esomeprazole via asymmetric oxidation of the corresponding, prochiral sulfide in the presence of a catalytic complex derived from titanium(IV) isopropoxide and two different chiral ligands, diethyl D-tartrate and (R)-N,N-dimethyl-1-phenylethanamine.
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