Journal
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
Volume 37, Issue 5, Pages 619-625Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1068162011050086
Keywords
triterpenoids; betulin; ketoximes; cyanoethylation; antiviral; antitubercular activity
Funding
- Russian Foundation for Basic Research [08-03-00868]
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Development of the functionalization of triterpenoids to A-secoamidoximes, A-secomethylenamines, and branched 3-(3-aminopropylamino)-3-(3-aminopropoxy)amidoximes is illustrated by the betulonic acid ketoxime. An effective way to get of the derivatives of 20,29-dihydrolupanes using diborane is suggested. The antiviral and antituberculosis activity data of some compounds are presented.
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