Journal
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
Volume 37, Issue 1, Pages 4-16Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1068162011010092
Keywords
interactomics; protein-protein interactions; bioinformatics; proteomics; genomic technologies; molecular fishing; optical biosensor; protein mass spectrometry
Funding
- Russian Academy of Medical Sciences
- Russian Foundation for Basic Research [09-04-12127-ofi_m, 10-04-13304-RT_omi]
- RF State [14.740.11.0761, 16.740.11.0372]
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Studies of protein-protein interactions are justified by the necessity of studying the functions of proteins which usually constitute stable or dynamic protein complexes in living organisms. A brief description and a comparative evaluation of the most widely used methods of protein interactomics are given in the present review.
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