4.0 Article

New 4,4-difluoro-3a,4a-diaza-s-indacene (BODIPY)-labeled sphingolipids for membrane studies

Journal

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
Volume 36, Issue 4, Pages 508-511

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1068162010040096

Keywords

fluorescent lipid probes; BODIPY; synthesis; membrane studies

Funding

  1. Russian Foundation for Basic Research [09-04-00313, 09-04-90423]

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The synthesis of a series of new fluorescently labeled sphingolipids containing a 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl (Me(4)-BODIPY-8) group at the omega-position of a fatty acyl residue is described. The obtained probes were used in studies of biological and model membrane systems.

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