4.5 Review

Acyl Meldrum's acid derivatives: application in organic synthesis

Journal

RUSSIAN CHEMICAL REVIEWS
Volume 83, Issue 7, Pages 620-637

Publisher

TURPION LTD
DOI: 10.1070/RC2014v083n07ABEH004441

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This review is focused on an important class of Meldrum's acid derivatives commonly known as acyl Meldrum's acids. The preparation methods of these compounds are considered including the recently proposed and rather rarely used ones. The chemical properties of acyl Meldrum's acids are described in detail, including thermal stability and reactions with various nucleophiles. The possible mechanisms of these transformations are analyzed.

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