4.1 Article

Synthesis of tetrazolodiazepines by a five-centered four-component azide Ugi reaction. Scope and limitations

Journal

RUSSIAN CHEMICAL BULLETIN
Volume 61, Issue 8, Pages 1609-1615

Publisher

SPRINGER
DOI: 10.1007/s11172-012-0214-3

Keywords

azide; 1,4-benzodiazepines; Ugi reaction; tetrazolodiazepines; isonitriles

Funding

  1. Russian Foundation for Basic Research [10-03-00243-a]

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Tetrazolo[1,5-a][1,4]benzodiazepines were obtained by an efficient azide five-centered four-component Ugi reaction, which used ketones, sodium azide, ammonium chloride, and the corresponding isonitrile. Scope and limitations of this multi-component reaction were considered.

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