Journal
RUSSIAN CHEMICAL BULLETIN
Volume 60, Issue 4, Pages 760-763Publisher
SPRINGER
DOI: 10.1007/s11172-011-0117-8
Keywords
marine-derived fungus Penicillium glabrum; Penicillium implicatum; styryl lactones; diphenyl ketones; protein Hsp70
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Funding
- Russian Foundation for Basic Research [09-04-00388, 08-04-00289]
- Presidium of the Russian Academy of Sciences
- Federal Agency for Science and Innovations of the Russian Federation [02.518.11.7169]
- Council on Grants of the President of the Russian Federation [NSh-3531.2010.4]
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The new styrylpyrone derivative, viz. 4-methoxy-3-methylgoniothalamin (1), and the known compound sulochrin were isolated from the marine-derived fungi Penicillium glabrum and P. implicatum. The structure of compound 1 was determined by X-ray diffraction, 2D NMR spectroscopy, and high-resolution mass spectrometry. It was shown for the first time that sulochrin increases expression of the protein Hsp70.
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