Journal
RNA
Volume 18, Issue 12, Pages 2118-2127Publisher
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1261/rna.035949.112
Keywords
RIG-I activation; dsRNA PAMPs; crystal and cocrystal X-ray structures
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A series of high-resolution crystal structures of RIG-I and RIG-I: dsRNA cocrystals has recently been reported. Comparison of these structures provides considerable insight into how this innate immune pattern recognition receptor is activated upon detecting and binding a certain class of viral RNAs.
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