Journal
PATIENT PREFERENCE AND ADHERENCE
Volume 9, Issue -, Pages 759-765Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/PPA.S81509
Keywords
cord blood transplantation; mesenchymal stem cell; aplastic anemia
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Funding
- National Natural Science Foundation of People's Republic of China [81170492, 81370673]
- National High Technology Research and Development Program 863 of People's Republic of China [2012AA022703]
- National Key Basic Research Program 973 of People's Republic of China [2010CB732404]
- Key Medical Projects of Jiangsu Province [BL2014078]
- Key Discipline of Jiangsu Province
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Delayed hematopoietic recovery and increased rate of engraftment failure limit the use of umbilical cord blood transplantation (UCBT). We describe a case of severe aplastic anemia treated by UCBT combined with mesenchymal stem cells. Our case reveals that infusing mesenchymal stem cells early (about 40 days) after UCBT may promote hematopoietic recovery. This experience will guide clinical scientists, especially hematologists, to deal with similar situations and encourage them to widen this strategy.
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