Journal
RHEUMATOLOGY INTERNATIONAL
Volume 29, Issue 10, Pages 1213-1217Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00296-008-0774-6
Keywords
Wegener's granulomatosis; Diabetes insipidus; Pituitary
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Wegener's granulomatosis (WG) is a necrotizing systemic vasculitis that any organ system can be involved in. We report a patient who was hospitalized with recurrent nodules in pulmonary computed tomograph and symptoms such as intermitted fever, polydipsia, insensibility and pain on extremities. Laboratory investigation showed positive antineutrophil cytoplasmic antibody in a cytoplastic pattern. The histopathologic result of the lung nodule revealed multiloci necrosis of lung tissue accompanied with large amount of neutrophils. She was diagnosed as WG with multi-systemic involvements and almost recovered on 6 months' prednisone and cyclophosphamide treatment.
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