Journal
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
Volume 40, Issue 3, Pages 455-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rdc.2014.04.006
Keywords
Cutaneous lupus erythematosus; Discoid lupus erythematosus; Chemokine; Interferon-alpha; Cytokine
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Funding
- Senior Scientist award at CFRI
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Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the development of autoantibodies and immunologic attack of different organ systems, including the skin. This review aims to provide an overview of some of the pathogenic processes that may be important in the development of SLE, specifically cutaneous lupus erythematosus, and then illustrates how therapies might be tailored to modify these processes and treat disease.
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