Journal
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
Volume 34, Issue 4, Pages 1025-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rdc.2008.08.014
Keywords
Sjogren's syndrome; B cell; BAFF/BLyS; Rituximab
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B-cell hyperactivity has been recognized for a long time in Sjogren's syndrome. This B-cell activation is firstly polyclonal but can progress to monoclonal B-cell lymphoproliferation. This article addresses the therapeutic potential of B-cell modulation in Sjogren's syndrome.
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