4.1 Article

CHARACTERIZATION OF THE MOLLUSCICIDAL ACTIVITY OF Bauhinia variegata AND Mimusops elengi PLANT EXTRACTS AGAINST THE Fasciola VECTOR Lymnaea acuminata

Journal

Publisher

INST MEDICINA TROPICAL SAO PAULO
DOI: 10.1590/S0036-46652012000300004

Keywords

Molluscicidal activity; Plant species; Extracts; Lymnaeid vector; Fasciola; Snail; Lymnaea acuminata; Bauhinia variegata; Mimusops elengi

Funding

  1. University Grants Commission (UGC), New Delhi, India [39/590-2010 (SR)]

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The molluscicidal activity of Bauhinia variegata leaf and Mimusops elengi bark was studied against vector snail Lymnaea acuminata. The toxicity of both plants was time and concentration-dependent. Among organic extracts, ethanol extracts of both plants were more toxic. Toxicity of B. variegata leaf ethanolic extract (96h LC50-14.4 mg/L) was more pronounced than M. elengi bark ethanolic extract (96h LC50-15.0 mg/L). The 24h LC50 of column purified fraction of B. variegata and M. elengi bark were 20.3 mg/L and 18.3 mg/L, respectively. Saponin and quercetin were characterized and identified as active molluscicidal component. Co-migration of saponin (Rf 0.48) and quercetin (Rf 0.52) with column purified bark of M. elengi and leaf of B. variegata on thin layer chromatography demonstrate same Rf value i.e. 0.48 and 0.52, respectively. The present study clearly indicates the possibility of using M. elengi and/or B. variegata as potent molluscicide.

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