Journal
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO
Volume 50, Issue 6, Pages 351-353Publisher
INST MEDICINA TROPICAL SAO PAULO
DOI: 10.1590/S0036-46652008000600008
Keywords
Chromoblastomycosis; Cladophialophora carrionii; Subcutaneous mycoses; Brazil
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A 73 year-old male farm laborer from a rural area presented a 15 year history of extensive tumoral lesions over his left leg. Histological studies of skin biopsy showed pseudoepitheliomatous hyperplasia and granulomatous chronic inflammatory process with muriform cells, confirming chromoblastomycosis (CBM). Cladophialophora carrionii was isolated in culture. Treatment with itraconazole 400 mg/day for 12 months resulted in complete remission of lesions. As far we aware, this is the first case report of CBM caused by Cladophialophora carrionii in Rio de Janeiro State, Brazil.
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