Journal
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
Volume 41, Issue 1, Pages 76-78Publisher
SOC BRASILEIRA MEDICINA TROPICAL
DOI: 10.1590/S0037-86822008000100015
Keywords
capsule-deficient Cryptococcus; mucicarmine; Fontana-Masson
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A case of cryptococcosis due to capsule- deficient Cryptococcus is presented, in which culturing of the clinical specimen and tests for capsular antigen in cerebrospinal fluid and serum were negative. The histopathological techniques evaluated were hematoxylin- eosin, Grocott methenamine silver, Mayer's mucicarmine and Fontana- Masson. The diagnosis of cryptococcosis due to capsule- deficient Cryptococcus was confirmed by means of the Fontana- Masson technique and by direct immunofluorescence. The potential of the histochemical techniques is discussed.
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