Related references
Note: Only part of the references are listed.Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease
D. J. R. Lane et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
Mechanistic and regulatory aspects of intestinal iron absorption
Sukru Gulec et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2014)
How Are Cytochrome b561 Electron Currents Controlled by Membrane Voltage and Substrate Availability?
Cristiana Picco et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Mouse divalent metal transporter 1 is a copper transporter in HEK293 cells
Miguel Arredondo et al.
BIOMETALS (2014)
Molecular liaisons between erythropoiesis and iron metabolism
Leon Kautz et al.
BLOOD (2014)
Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Peilong Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Iron Transport through Ferroportin Is Induced by Intracellular Ascorbate and Involves IRP2 and HIF2 alpha
Nathalie Scheers et al.
NUTRIENTS (2014)
The physiological functions of on regulatory proteins in iron homeostasis - an update
De-Liang Zhang et al.
FRONTIERS IN PHARMACOLOGY (2014)
The IRP/IRE system in vivo: insights from mouse models
Nicole Wilkinson et al.
FRONTIERS IN PHARMACOLOGY (2014)
Special delivery: distributing iron in the cytosol of mammalian cells
Caroline C. Philpott et al.
FRONTIERS IN PHARMACOLOGY (2014)
Cytochromes b561: Ascorbate-Mediated Trans-Membrane Electron Transport
Han Asard et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action
Alfons Lawen et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Electron Transfer Reactions of Candidate Tumor Suppressor 101F6 Protein, a Cytochrome b561 Homologue, with Ascorbate and Monodehydroascorbate Radical
Mariam C. Recuenco et al.
BIOCHEMISTRY (2013)
Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism
Darius J. R. Lane et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions
Maria Mastrogiannaki et al.
BLOOD (2013)
IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation
Nicole Wilkinson et al.
BLOOD (2013)
Regulation of erythropoiesis by hypoxia-inducible factors
Volker H. Haase
BLOOD REVIEWS (2013)
The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption
Sheila A. Anderson et al.
CELL METABOLISM (2013)
Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α
Manik C. Ghosh et al.
CELL METABOLISM (2013)
Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins
Oliver Stehling et al.
CELL METABOLISM (2013)
Dihydrolipoic acid reduces cytochrome b561 proteins
Alajos Berczi et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2013)
Transcription Factors Sp1 and Hif2α Mediate Induction of the Copper-transporting ATPase (Atp7a) Gene in Intestinal Epithelial Cells during Hypoxia
Liwei Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Hepcidin Bound to α2-Macroglobulin Reduces Ferroportin-1 Expression and Enhances Its Activity at Reducing Serum Iron Levels
Michael Li-Hsuan Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Divalent metal transporter 1 (Dmt1) Mediates Copper Transport in the Duodenum of Iron-Deficient Rats and When Overexpressed in Iron-Deprived HEK-293 Cells
Lingli Jiang et al.
JOURNAL OF NUTRITION (2013)
Copper Deficiency Leads to Anemia, Duodenal Hypoxia, Upregulation of HIF-2α and Altered Expression of Iron Absorption Genes in Mice
Pavle Matak et al.
PLOS ONE (2013)
Out of Balance-Systemic Iron Homeostasis in Iron-Related Disorders
Andrea U. Steinbicker et al.
NUTRIENTS (2013)
Hepcidin and iron homeostasis
Tomas Ganz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Ferroportin-mediated iron transport: Expression and regulation
Diane M. Ward et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Mammalian iron metabolism and its control by iron regulatory proteins
Cole P. Anderson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
Tracey A. Rouault
DISEASE MODELS & MECHANISMS (2012)
Duodenal Reductase Activity and Spleen Iron Stores Are Reduced and Erythropoiesis Is Abnormal in Dcytb Knockout Mice Exposed to Hypoxic Conditions
Jeehyea Choi et al.
JOURNAL OF NUTRITION (2012)
Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2α) in intestinal epithelial cells
Liwei Xie et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Duodenal cytochrome b (Cybrd 1) and HIF-2α expression during acute hypoxic exposure in mice
Gladys O. Latunde-Dada et al.
EUROPEAN JOURNAL OF NUTRITION (2011)
Quercetin-iron chelates are transported via glucose transporters
Evangelia Vlachodimitropoulou et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice
Matthew Taylor et al.
GASTROENTEROLOGY (2011)
Hypoxia-Mediated Biological Control
Jessica Cassavaugh et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
Iron Homeostasis and Its Interaction with Prolyl Hydroxylases
David R. Mole
ANTIOXIDANTS & REDOX SIGNALING (2010)
A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane
Darius J. R. Lane et al.
BIOCHEMICAL JOURNAL (2010)
Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron
Darius J. R. Lane et al.
BIOCHEMICAL JOURNAL (2010)
Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
Paolo Arosio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
Two to Tango: Regulation of Mammalian Iron Metabolism
Matthias W. Hentze et al.
CELL (2010)
Iron Regulatory Proteins Secure Mitochondrial Iron Sufficiency and Function
Bruno Galy et al.
CELL METABOLISM (2010)
Quercetin is a substrate for the transmembrane oxidoreductase Dcytb
Evangelia Vlachodimitropoulou et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Intestinal Iron Absorption: Regulation by Dietary a Systemic Factors
Paul A. Sharp
INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH (2010)
Ctr1 Is an Apical Copper Transporter in Mammalian Intestinal Epithelial Cells in Vivo That Is Controlled at the Level of Protein Stability
Yasuhiro Nose et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
Des R. Richardson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Hepcidin, the hormone of iron metabolism, is bound specifically to α-2-macroglobulin in blood
Gabriela Peslova et al.
BLOOD (2009)
Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis
Gregg L. Semenza
BLOOD (2009)
A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis
Clare C. Constantine et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Intestinal Hypoxia-inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency
Yatrik M. Shah et al.
CELL METABOLISM (2009)
Regulation of Intestinal Iron Absorption: The Mucosa Takes Control?
Robert J. Simpson et al.
CELL METABOLISM (2009)
Ascorbate and plasma membrane electron transport-Enzymes vs efflux
Darius J. R. Lane et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
HIF-2α, but not HIF-1α, promotes iron absorption in mice
Maria Mastrogiannaki et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Differing expression of genes involved in non-transferrin iron transport across plasma membrane in various cell types under iron deficiency and excess
Kamila Balusikova et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
Function and biogenesis of iron-sulphur proteins
Roland Lill
NATURE (2009)
An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis
Ameen A. Salahudeen et al.
SCIENCE (2009)
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
Ajay A. Vashisht et al.
SCIENCE (2009)
Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network
Martina U. Muckenthaler et al.
Annual Review of Nutrition (2008)
The role of Dcytb in iron metabolism: an update
Andrew T. McKie
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Recombinant expression and initial characterization of the putative human enteric ferric reductase Dcytb
Susanne Ludwiczek et al.
BIOCHEMISTRY (2008)
Functional characterization of human duodenal cytochrome b (Cybrd1):: Redox properties in relation to iron and ascorbate metabolism
Jonathan S. Oakhill et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)
Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum
Bruno Galy et al.
CELL METABOLISM (2008)
Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro
Steven Wyman et al.
FEBS LETTERS (2008)
Non-transferrin iron reduction and uptake are regulated by transmembrane ascorbate cycling in K562 cells
Darius J. R. Lane et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Duodenal cytochrome B expression stimulates iron uptake by human intestinal epithelial cells
Gladys O. Latunde-Dada et al.
JOURNAL OF NUTRITION (2008)
Small-Molecule Inhibitors of HIF-2a Translation Link Its 5′UTR Iron-Responsive Element to Oxygen Sensing
Michael Zimmer et al.
MOLECULAR CELL (2008)
Involvement of 101F6, a homologue of cytochrome b561, in the reduction of ferric ions
Atsushi Mizutani et al.
JOURNAL OF BIOCHEMISTRY (2007)
Histidine cycle mechanism for the concerted proton/electron transfer from ascorbate to the cytosolic haem b centre of cytochrome b561:: A unique machinery for the biological transmembrane electron transfer
Nobuyuki Nakanishi et al.
JOURNAL OF BIOCHEMISTRY (2007)
Uptake and reduction of α-lipoic acid by human erythrocytes
James M. May et al.
CLINICAL BIOCHEMISTRY (2007)
The molecular mechanism of hepcidin-mediated ferroportin down-regulation
Ivana De Domenico et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Regulation of systemic iron homeostasis: how the body responds to changes in iron demand
Gregory J. Anderson et al.
BIOMETALS (2007)
Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency
Mayka Sanchez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
The hypoxia-inducible factor 2α N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo
Qin Yan et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Iron uptake and metabolism in the new millennium
Louise L. Dunn et al.
TRENDS IN CELL BIOLOGY (2007)
Vitamin C - Biosynthesis, recycling and degradation in mammals
Carole L. Linster et al.
FEBS JOURNAL (2007)
Human erythrocyte membranes contain a cytochrome b561 that may be involved in extracellular ascorbate recycling
Dan Su et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
An ascorbate-reducible cytochrome b561 is localized in macrophage lysosomes
De-liang Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells
Juan P. Liuzzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Stimulation of non-transferrin iron uptake by iron deprivation in K562 cells
Jan Kovar et al.
BLOOD CELLS MOLECULES AND DISEASES (2006)
Duodenal cytochrome b:: a novel ferrireductase in airway epithelial cells
Jennifer L. Turi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Three mammalian cytochromes b561 are ascorbate-dependent ferrireductases
Dan Su et al.
FEBS JOURNAL (2006)
The role of iron regulatory proteins in mammalian iron homeostasis and disease
Tracey A. Rouault
NATURE CHEMICAL BIOLOGY (2006)
Docking studies show that D-glucose and quercetin slide through the transporter GLUT1
P Cunningham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The role of duodenal cytochrome b in intestinal iron absorption remains unclear
DM Frazer et al.
BLOOD (2005)
Cytochrome b561 protein family: Expanding roles and versatile transmembrane electron transfer abilities as predicted by a new classification system and protein sequence motif analyses
M Tsubaki et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)
Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice
H Gunshin et al.
BLOOD (2005)
Altered body iron distribution and rmicrocytosis in mice deficient in iron regulatory protein 2 (IRP2)
B Galy et al.
BLOOD (2005)
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
SS Cooperman et al.
BLOOD (2005)
Myricetin, quercetin and catechin-gallate inhibit glucose uptake in isolated rat adipocytes
P Strobel et al.
BIOCHEMICAL JOURNAL (2005)
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
A Donovan et al.
CELL METABOLISM (2005)
Duodenal ascorbate levels are changed in mice with altered iron metabolism
B Atanasova et al.
JOURNAL OF NUTRITION (2004)
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
EG Meyron-Holtz et al.
EMBO JOURNAL (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
The molecular basis of copper and iron interactions
P Sharp
PROCEEDINGS OF THE NUTRITION SOCIETY (2004)
Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice
HJ Chen et al.
BLOOD (2004)
Superoxide-dependent iron uptake a new role for anion exchange protein 2
AJ Ghio et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)
Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases
JD Vargas et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2003)
Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
SY Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption
DM Frazer et al.
GUT (2003)
Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolism
GO Latunde-Dada et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
Uptake, recycling, and antioxidant actions of α-lipoic acid in endothelial cells
W Jones et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Characterization of a cytochrome b558 ferric/cupric reductase from rabbit duodenal brush border membranes
M Knöpfel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
CH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
An iron-regulated ferric reductase associated with the absorption of dietary iron
AT McKie et al.
SCIENCE (2001)
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
T LaVaute et al.
NATURE GENETICS (2001)
Intracellular accumulation of ascorbic acid is inhibited by flavonoids via blocking of dehydroascorbic acid and ascorbic acid uptakes in HL-60, U937 and Jurkat cells
JB Park et al.
JOURNAL OF NUTRITION (2000)
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
AT McKie et al.
MOLECULAR CELL (2000)