Journal
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
Volume 20, Issue 2, Pages 140-146Publisher
SPRINGERNATURE
DOI: 10.1590/S0102-695X2010000200001
Keywords
Schinus terebenthifolius; Myracrodruon urundeuva; pH; intestinal transit; gastric ulcer; gastric hemorrhage
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Schinus terebinthifolius Raddi and the Myracrodruon urundeuva Allemao were evaluated in rats and mice for antiulcer effects, as these two plants are widely used in Brazil for gastric ulcer treatment. Extracts of the plants showed a marked protective effect against gastric ulcerations induced by immobilization stress at low temperature in rats. They also showed an increase in the pH and volume of the gastric contents, and reduction in gastric hemorrhage in rats, and decrease in intestinal transit in mice, even at the low doses of 3.4 mg/kg (1/4 of the dose used by humans).
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