Journal
REVIEW OF SCIENTIFIC INSTRUMENTS
Volume 84, Issue 11, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.4828656
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Funding
- RIKEN
- X-ray Free Electron Laser Priority Strategy Program by MEXT
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This paper describes the development of a versatile coherent x-ray diffraction microscope capable of imaging biological specimens in solution. The microscope is a flexible platform accommodating various conditions, from low vacuum (10(-2) Pa) to helium gas filled ambient pressure. This flexibility greatly expands the application area, from in situ materials science to biology systems in their native state, by significantly relaxing restrictions to the sample environment. The coherent diffraction microscope has been used successfully to image a yeast cell immersed in buffer solution. We believe that the design of this coherent diffraction microscope can be directly adapted to various platforms such as table top soft x-ray laser, synchrotron x-ray sources, and x-ray free electron laser with minor relevant adjustments. (C) 2013 AIP Publishing LLC.
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