Journal
REVIEW OF SCIENTIFIC INSTRUMENTS
Volume 84, Issue 1, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.4772396
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Funding
- Dutch Technology Foundation STW, the applied science division of NWO
- Technology Program of the Ministry of Economic Affairs [OTP 11956]
- Dutch national program COMMIT
- Netherlands Proteomics Center
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In-vacuum active pixel detectors enable high sensitivity, highly parallel time-and space-resolved detection of ions from complex surfaces. For the first time, a Timepix detector assembly was combined with a secondary ion mass spectrometer for microscope mode secondary ion mass spectrometry (SIMS) imaging. Time resolved images from various benchmark samples demonstrate the imaging capabilities of the detector system. The main advantages of the active pixel detector are the higher signal-to-noise ratio and parallel acquisition of arrival time and position. Microscope mode SIMS imaging of biomolecules is demonstrated from tissue sections with the Timepix detector. (C) 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4772396]
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