Journal
RETROVIROLOGY
Volume 5, Issue -, Pages -Publisher
BMC
DOI: 10.1186/1742-4690-5-118
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Funding
- NIH Bench-to-Bedside Program
- Intramural AIDS Targeted Anti-viral Program (IATAP)
- NIAID
- NIH
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MicroRNAs ( miRNAs) play diverse roles in regulating cellular and developmental functions. We have profiled the miRNA expression in peripheral blood mononuclear cells from 36 HIV-1 seropositive individuals and 12 normal controls. The HIV-1-positive individuals were categorized operationally into four classes based on their CD4+ T-cell counts and their viral loads. We report that specific miRNA signatures can be observed for each of the four classes.
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