Journal
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
Volume 187, Issue 1, Pages 5-10Publisher
ELSEVIER
DOI: 10.1016/j.resp.2013.01.013
Keywords
Cigarette smoking; Inflammation; NF-kB; Oral health; COPD; IBD
Categories
Funding
- Rappaport Institute
- Krol Foundation of Barnegat, NJ
- Myers-JDC-Brookdale Institute of gerontology and human development
- ESHEL - the association for planning and development of services for the aged in Israel
Ask authors/readers for more resources
Despite the significant health risks resulting from tobacco use, the prevalence of smokers worldwide remains high. Cigarette smoking is one of the major sources of toxic chemical exposure to humans and is the greatest cause of preventable illnesses and premature death. The adverse consequences of smoking in various pathologies are mediated by its effects on the immune-inflammatory system. In this review, we aim to explore the effects of cigarette smoking on the inflammatory response and molecular mechanisms with emphasis on the nuclear factor kappa B (NF-kB) pathway. The effects of smoking on various inflammatory pathologies will be discussed, focusing on oral diseases, airway inflammation, chronic obstructive pulmonary disease (COPD) and inflammatory bowel diseases (IBD). (c) 2013 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available